Most formaldehyde produced in the United States is for the manufacture of resins, such as urea-formaldehyde, used to make the adhesives for pressed wood products, such as particleboard, furniture, paneling, cabinets, and other products. The general use made of formaldehyde—especially in the form of the commercial 40 per cent. (Formaldehyde is a natural product of single-carbon metabolism.) The following resources provide information about occupational exposure to formaldehyde. It is commonly used in producing household products, such as adhesives, coatings, dishwashing liquids, fabric softener, glues and paper products. Visit NIOSH’s page on Managing Chemical Safety in the Workplace to learn more about controlling chemical workplace exposures. Preservatives used in some medicines and cosmetics may contain formaldehyde. There are limited data available on the direct effects of exposure to formaldehyde during pregnancy. It is used in the production of fertilizer, paper, plywood, and some resins. Philadelphia, PA 19104, Pharmacokinetic modeling as an approach to assessing the safety of residual formaldehyde in infant vaccines, Diphtheria, Tetanus and Pertussis Vaccines, Haemophilus influenzae type B (Hib) Vaccine, Japanese Encephalitis Virus (JEV) Vaccine, Vaccine- and Vaccine Safety-Related Q&A Sheets, “Special Topics” Online Series Q&A Sheets, Antibody-dependent enhancement (ADE) and vaccines, Autoimmune/Inflammatory Syndrome Induced by Adjuvants, Vaccine Considerations for Specific Groups, Vaccine Considerations for New and Expectant Moms, Evaluating Scientific Information and Studies, Licensure, Recommendations and Requirements. According to the United States Environmental Protection Agency (EPA), formaldehyde is a colorless, flammable, and strong-smelling chemical. Aside from ALS risk or other nervous system consequences, formaldehyde is a respiratory irritant that causes chest pain, shortness of breath, … And if you don't drop dead from respiratory failure or fall into a coma, drinking even tiny doses of concentrated formaldehyde can bring convulsions, stomach pain, diarrhea, vomiting, vertigo and a host of other very bad side effects [source: U.S. National Library of Medicine]. Skin Contact. Formaldehyde exposure to the skin can cause irritation and may burn the skin. 4 Health Effects of Formaldehyde Formaldehyde can cause irritation of the skin, eyes, nose, and throat. CDC twenty four seven. Formaldehyde has been found in at least 29 of the 1,669 National Priorities List sites identified by the Environmental Protection Agency (EPA). Formaldehyde irritates the nose, eyes, and throat. This quantity of formaldehyde is considered to be safe for two reasons: Quantity per dose: ≤ 0.005 mg – 0.1 mg, Quantity per dose: ≤ 0.005 mg – ≤ 0.1 mg, Quantity per dose: < 0.0075 mg (pediatric); < 0.015 mg (adult and dialysis formulations). The Vaccine Education Center staff regularly reviews materials for accuracy. Formaldehyde, a major component in embalming fluid, is legal to purchase and possess and has become popular due to its euphoric properties. Formaldehyde exposure is toxic to the brains of mammals, but the mechanism remains unclear. When produced in the atmosphere by the action of sunlight and oxygen on atmospheric methane and other hydrocarbons, it becomes part of smog. Repeated exposure to formaldehyde can possibly lead to cancer. The authors estimated the levels of formaldehyde in blood and total body water following exposure to formaldehyde-containing vaccines and compared them with endogenous background levels. 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